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Rated 4.7 | 480 Reviews

Stabilized R-ALA 600mg – Pure R-Form, Slow-Release & Gentle on the Stomach

Tried ALA before and felt nothing, or your stomach wouldn't keep it down? Most ALA on the shelf is half a mirror-image form your body doesn't make, released all at once. Ours is 600 mg of only the R-form, in a slow-release capsule built to be gentle on the stomach.

  • Pure R-form, not the 50/50 mix most "ALA" is
  • Slow-release granules, no all-at-once acid hit
  • Helps ease burning, tingling and numbness
  • Stabilized, so the fragile R-form stays intact
  • 600 mg daily, the amount studied in the clinical trials
  • May also support healthy fasting blood sugar
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How to use +

Take 3 capsules once daily with a meal— breakfast or lunch is ideal. That's the full 600mg clinical dose of stabilized R-Alpha Lipoic Acid your nerves need, delivered the way German doctors have prescribed it for decades.

Our slow-release capsule is designed to absorb well even when taken with food, so you don't have to worry about timing it perfectly — and it's gentle on the stomach. Take it daily without skipping. The trials that backed this formula measured results over weeks and months of consistent use, not days. Stay with it.

Can R-ALA help with non-diabetic neuropathy? +

R-ALA isn’t exclusive to people with diabetes. It supports the body’s antioxidant defenses and healthy nerve function, so it may also be relevant for neuropathy caused by other factors.

However, most clinical research has focused on diabetic peripheral neuropathy, while evidence for other types of neuropathy is still limited and mixed.

Are there any side effects? +

R-ALA is generally well tolerated, and most people take it without any issues. Unlike standard capsules that release the entire dose at once, our slow-release granules deliver R-ALA gradually. This is designed to be gentler on the stomach and help minimize occasional digestive discomfort. Individual tolerance can still vary.

Because R-ALA may lower blood sugar, speak with your healthcare provider if you take blood-sugar-lowering medication.

What about Stomach Burning? +

Some standard ALA supplements may cause occasional stomach burning or heartburn because the full dose is released at once.

Our capsules use slow-release granules, which gradually release the R-ALA instead of dumping the entire dose into your stomach at once.

This is designed to be gentler on the stomach and minimize digestive discomfort. Most people tolerate R-ALA well, although individual responses can vary.

Ingredients +

Each capsule contains 200mg of stabilized R-Alpha Lipoic Acid in its pure R-form — the biologically active form your nerve cells actually recognize. Delivered in a slow-release capsule for support over 8 hours. No fillers. No proprietary blends. No racemic S-form that blocks the active ingredient from doing its job. What you see on the label is exactly what is in the capsule at the exact dose the clinical trials used.

How long before I notice a difference? +

R-ALA is not an instant pain reliever—it works best when taken consistently.

In clinical studies of oral alpha-lipoic acid for diabetic neuropathy, improvements were assessed after approximately 3–5 weeks.

Some people may notice changes sooner, while others may require longer, and results vary from person to person.

60-Day Guarantee +

We offer a 60-day money-back guarantee. If you don't feel a meaningful difference after consistent use we will refund you in full — no questions asked.

Shipping & Returns +

We offer tracked shipping on all orders.

All orders are processed by our careful fulfilment team within 24 business hours.

We are currently experiencing high volume of orders so delivery times, depending on your location, range from 5-13 business days.

We've made returning products super easy. Simply contact us support@rootofnature.com and we'll handle everything.

Backed by 3 major clinical trials

Stabilized R-ALA 600mg - Advanced Nerve Support for Burning, Tingling & Numbness
Excellent 4.6 | 480 reviews

Stabilized R-ALA 600mg - Advanced Nerve Support for Burning, Tingling & Numbness

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Make The Burning, Tingling And Numbness Finally Back Off

Not another bottle in the drawer. The form your body actually makes, released slowly so your stomach can keep it down, at the dose the trials studied, and taken long enough to find out.

Make The Burning, Tingling And Numbness Finally Back Off

Not another bottle in the drawer. The form your body actually makes, released slowly so your stomach can keep it down, at the dose the trials studied, and taken long enough to find out.
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What To Expect – And How To Know It's Working

You've done the careful trial before and seen nothing. Here is what to watch for this time.

Week 1-2

Your stomach should stay calm

This is the window where standard ALA usually bites back with heartburn or nausea. Our slow-release granules let the dose out gradually, so most people take it with a meal and notice nothing in the stomach. In the feet, not much yet either, and that is normal.

Week 3-4

The first shift

This is where people most often notice the burning and tingling start to quiet down. In the clinical trials, symptom scores were measured at 3 to 5 weeks. Keep a short note each evening: burning 1-10, tingling 1-10, hours slept. Then you can see it in black and white instead of guessing.

Week 5-8

Proof you can read

Look back at your notes. Lower numbers, fewer bad nights, a little more feeling in the feet. This is the honest test most people never get to give ALA, because the wrong form or an upset stomach made them quit first.

Beyond 8 Weeks

Keep the ground you've won

In the 4-year NATHAN 1 trial, people taking 600 mg of ALA a day had leg nerve scores that held up better than on placebo. The goal is not one good week. It is stopping the slow creep, and keeping it stopped.

The Only Choice That Actually Works

Most ALA sold in America is a 50/50 mix: half the R-form your body makes, half a synthetic mirror image it doesn't. Released all at once, it is also what gives so many people heartburn. Root of Nature is pure, stabilized R-ALA in slow-release granules.

The Only Choice That Actually Works

Most ALA sold in America is a 50/50 mix: half the R-form your body makes, half a synthetic mirror image it doesn't. Released all at once, it is also what gives so many people heartburn. Root of Nature is pure, stabilized R-ALA in slow-release granules.

Us
Root of Nature
Others
Generic Nerve Supplements
Pure R-Form Only
Full 600mg Clinical Dose
Stabilized Form
Fat-Soluble Delivery
No Stomach Burning

60-Day Money-Back Guarantee

We're so confident in the quality of our product that we offer a satisfaction guarantee. If you're not completely satisfied with your purchase, simply return the item within 60 days for a full refund.

Add to Cart
100% Satisfaction
Fast Shipping
Easy Returns

60-Day Money-Back Guarantee

We're so confident in the quality of our product that we offer a satisfaction guarantee. If you're not completely satisfied with your purchase, simply return the item within 60 days for a full refund.

Add to Cart
100% Satisfaction
Fast Shipping
Easy Returns

Frequently Asked Questions

Find answers to common questions about our products, shipping, returns, and more.

I already tried ALA and it did nothing. Why would this be different? +

Most "Alpha Lipoic Acid" sold in America, including the top sellers at GNC, Walmart and Amazon, is the cheap racemic form: a 50/50 mix of the natural R-form your body makes and a synthetic S-form it doesn't. That's the version most people try, feel little from, and write off as "ALA doesn't work."

Root of Nature is pure, stabilized R-ALA at 600 mg a day, the same daily amount the major clinical trials used, in a slow-release capsule whose granules let the dose out gradually instead of all at once. That is what makes it gentle on the stomach, where standard ALA often causes heartburn and nausea.

My stomach couldn't take ALA. Will this be the same? +

Heartburn, nausea and a burning throat are the most common reasons people quit ALA, usually within days and before it ever had a chance to help. They happen because a regular capsule dumps the whole acidic dose into your stomach at once.

Our capsule is filled with slow-release granules that let the R-ALA out gradually over hours. Take it with a meal and most people notice nothing in the stomach. Individual tolerance can still vary, and if it doesn't sit right with you, our 60-day guarantee has you covered.

I already take R-ALA. What's different here? +

Plain R-ALA is fragile: heat and light make it break down, and a normal capsule still releases it all at once. Ours is stabilized R-ALA, so the R-form stays intact, and it comes in slow-release granules for about 8 hours of steady supply instead of a short spike.

And it's the full 600 mg a day, the amount used in the major trials. Many R-ALA products give you far less.

Does it actually work or is this just good marketing? +

Fair question, and one we'd be asking too. Don't take our word for it. Look at the research on alpha lipoic acid itself.

In the SYDNEY 2 trial (2006), people with diabetic nerve damage took 600 mg of ALA by mouth once a day. After 5 weeks their symptom score (burning, pain, tingling, numbness) had dropped by 51%, versus 32% on placebo. In NATHAN 1, a 4-year trial with 460 patients, leg nerve scores held up better on 600 mg a day than on placebo. In Germany, ALA has been a licensed pharmacy medicine for diabetic nerve symptoms for decades.

Those trials used standard ALA, and half of standard ALA is a mirror-image form your body doesn't make. Root of Nature gives you the same 600 mg, as only the R-form, in a slow-release capsule. We didn't run those studies. We simply built the formula around them.

Does it affect blood sugar? +

It may. Studies have found that alpha lipoic acid can support healthy fasting blood sugar and insulin sensitivity, which is good news for many people with nerve problems.

It also means: if you take insulin or other blood-sugar medication, talk to your doctor before you start, and keep checking your numbers as usual.

4.7  480 Reviews